Ion Exchange Resins Are Classified By Physical Structure

Gel resin has a relatively dense cross-linked structure, its pore size is small, usually less than 2nm, this kind of resin is suitable for the separation of small molecules, such as inorganic salts, organic acids and so on. Due to the small pore size, the gel resin is prone to diffusion limitation when adsorbing large molecules, resulting in a slow exchange rate.

Macroporous resins have larger pore sizes, usually between tens of nanometers and hundreds of nanometers. The crosslinking structure of this kind of resin is relatively loose, which is conducive to the diffusion and exchange of macromolecular substances in the resin. Therefore, macroporous resins are particularly suitable for the separation of macromolecular substances, such as proteins, nucleic acids and other biological macromolecules.