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WebSep 24, 2020 · The column used is a weak cation exchanger which has carboxylic acid groups that have an inherent buffering capacity. With a 5 mM buffer concentration, the pH drops uncontrollably...
WebJan 1, 2018 · 1. Using a high ionic strength buffer. The large number of ions within the buffer will disrupt the analyte–sorbent interactions. 2. Altering the pH through addition...
WebPolymeric material for the retention of weak acids Surface area 550 to 750m2/g; Particle size 40 to 60µm; Pore size 60Å; Mixed mode Strong cation exchanger functionalized with quaternary groups....
WebJan 10, 2018 · Just as with anion exchangers, cation exchangers can be classified as either weak or strong. A weak cation exchanger is comprised of a weak acid that gradually loses its charge as...
WebAt neutral pH the carboxymethyl group is ionized as -CH2OCH2COO¯ so that CM- cellulose is negatively charged, so it is a weak cation exchanger. DEAE-cellulose contains an...