Macroporous resin is also called porous resin, which is a kind of molecular polymer characterized by adsorption, separation and concentration of organic matter, and is prepared by a series of polymerization reactions of polymeric monomer and crosslinking agent, pore-causing agent, dispersant and other additives. After the pore-causing agent is removed, holes of different sizes and shapes are left in the resin, so the macroporous resin has a relatively high porosity, and the pore size is up to 1000 nanometers, so it is also called the macroporous adsorption resin.
Macroporous resin adsorption technology is a key link in the purification and purification of traditional Chinese medicine, but also an important step to improve the quality of traditional Chinese medicine, which directly affects the clinical efficacy of drugs. In the past 30 years, the method of water boiling and alcohol precipitation in China has been used to remove impurities, making Chinese medicine pharmaceutical technology lag behind the industrial level of pharmaceutical industry. The use of macroporous adsorption technology to remove impurities has three main advantages:
1, reduce the dose, improve the preparation level, the macroporous adsorption resin process can complete the two processes of impurity removal and concentration once, the dose is reduced, and the impurities are less;
2, moisture-proof, the Chinese patent medicine prepared by the macroporous adsorption resin process solves the industry pain points of the traditional process of moisture absorption, and effectively removes a large number of inorganic salts, mucous and other moisture absorption components of the water decoction;
3, shorten the production cycle, large hole resin process eliminates sedimentation, concentration and other time-consuming and laborious processes, save packaging and reduce costs.
The extracts obtained by macroporous resin adsorption separation process are small in volume, non-moisture absorption, especially suitable for particles, capsules, etc., making traditional Chinese medicine preparations modern preparations.